Volume 7, Issue 4, December 2019, Page: 182-192
Metabolic Syndrome Response to Different Physical – Exercise Protocols
Mariana Santoro Nakagaki, Center for Nutritional and Physical Exercise Metabolism, Department of Public Health, UNESP - Sao Paulo State University, School of Medicine, Botucatu, Brazil; Physical Exercise Graduate Joint Program, Londrina and Maringa State Universities, Londrina, Brazil
Hugo Tadashi Kano, Center for Nutritional and Physical Exercise Metabolism, Department of Public Health, UNESP - Sao Paulo State University, School of Medicine, Botucatu, Brazil; Pathology Graduate Program, School of Medicine, UNESP - Sao Paulo State University, Botucatu, Brazil
Roberto Carlos Burini, Center for Nutritional and Physical Exercise Metabolism, Department of Public Health, UNESP - Sao Paulo State University, School of Medicine, Botucatu, Brazil
Received: Nov. 9, 2019;       Accepted: Nov. 27, 2019;       Published: Dec. 4, 2019
DOI: 10.11648/j.ajss.20190704.19      View  193      Downloads  133
Abstract
Background: Metabolic syndrome (MetS) represents a growing public health problem throughout the world and, making sense with the epigenetic causes of MetS, lifestyle change seems yet, more clinically effective than drugs. Additionally to dietary adequacy, increased physical activity (LiSM) is considered the cornerstone of recommendations for the treatment of MetS. Previously it was found that different types of physical exercises led to different responses in reducing adiposity, hypertension and hyperglycemia. Now we aim to investigate the specific effect of four different physical-exercise protocols on MetS in a defined short time intervention of 10 weeks. Methods: A sample of 302 individuals (55.5 ± 10.8 years) from both genders was taken among (2013-2016) participants of the dynamic cohort "Move for Health" LiSM program. They were evaluated at baseline and after 10 weeks of supervised intervention with protocols of hydrognastics (HYD, aerobic), High Intensity Interval Training (HIT), resistance training in gym (GYM) and mixed walking-gym (MIX, 30 min of walking 60-80% HRmax and resistance). All groups received the same basic LiSM dietary counseling. The evaluation instruments were: International Physical Activity Questionnaire (IPAQ-long form-version 8); Healthy Eating Index (HEI), anthropometric, plasma biochemical analyses and physical fitness (flexibility, handgrip strength and treadmill cardiorespiratory capacity). MetS was diagnosed according to NCEP-ATP III (2005). The data were evaluated in continuous and categorized forms. Multiple comparison (moment versus protocol) was undertaken at the level of significance of 5%. Results: After 10-wk intervention, all protocols incremented the baseline fitness of VO2 max; flexibility (except in the HIT); muscle strength (only in GYM and MIX) and also, the level of physical activity in MIX. There was a 16.9% reduction in MetS, from 25.4% (HYD) to 12.7%(MIX), having HIT (21.5%) and GYM (16.2%), in between. Hyperglycemia (20.6%) and hypertension (15.9%) responded positively to all protocols, while the reduction of abdominal circumference discriminated the effectiveness of MIX and HYD in reducing MetS. Conclusion: At the same duration, prescribed protocols of HYD, HIT, GYM and MIX decreased MetS in different magnitude according to the MetS-component sensitivity to each protocol.
Keywords
Metabolic Syndrome, Lifestyle Modification, Physical-exercise Protocols
To cite this article
Mariana Santoro Nakagaki, Hugo Tadashi Kano, Roberto Carlos Burini, Metabolic Syndrome Response to Different Physical – Exercise Protocols, American Journal of Sports Science. Vol. 7, No. 4, 2019, pp. 182-192. doi: 10.11648/j.ajss.20190704.19
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Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Reference
[1]
Burini RC, Michelin E, Burini FHP, Moreto F, McLellan KCP. Behavioral risk factors and effects of lifestyle-modification on the metabolic syndrome in adults. A Brazilian community-based study. In: (Org.). ICMLGPAPG, editor. Handbook on Metabolic Syndrome: Classification, Risk Factors and Health Impact. 1. 1ed.: Nova Science Pub Inc. 2012. p. 1-413.
[2]
Gami AS, Witt BJ, Howard DE, Erwin PJ, Gami LA, Somers VK, et al. Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. J Am Coll Cardiol. 2007; 49 (4): 403-14.
[3]
Mottillo S, Filion KB, Genest J, Joseph L, Pilote L, Poirier P, et al. The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis. J Am Coll Cardiol. 2010; 56 (14): 1113-32.
[4]
Ford ES, Li C, Sattar N. Metabolic syndrome and incident diabetes: current state of the evidence. Diabetes Care. 2008; 31 (9): 1898-904.
[5]
Medina WL, Burini FHP, Pereira AF, Burini RC. Síndrome Metabólica. In: Daniel Magnoni; Celso Cukier. (Org.). Perguntas e respostas em nutrição clínica: Sao Paulo: Roca, 2ed. 2004, 171-8.
[6]
King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care. 1998; 21 (9): 1414-31.
[7]
Burini RC, Kano HT, Burini FHP, McLellan KCP. Metabolic Syndrome - From the Mismatched Evolutionary Genome with the Current Obesogenic Environment to the Lifestyle Modification as a Primary Care of Free-Living Adults in a Brazilian Community. In: Morton IJ, editor. Metabolic Syndrome: Clinical Aspects, Management Options and Health Effects. Nova Science Publ. (NY) 2016.
[8]
Carnethon MR, Loria CM, Hill JO, Sidney S, Savage PJ, Liu K, et al. Risk factors for the metabolic syndrome: the Coronary Artery Risk Development in Young Adults (CARDIA) study, 1985-2001. Diabetes Care. 2004; 27 (11): 2707-15.
[9]
Stensvold D, Tjonna AE, Skaug EA, Aspenes S, Stolen T, Wisloff U, et al. Strength training versus aerobic interval training to modify risk factors of metabolic syndrome. J Appl Physiol (1985). 2010; 108 (4): 804-10.
[10]
Marsola FC, Rinaldi AEM, Siqueira M, Portero-McLellan KC, Corrente JE, Burini RC. Association of dietary patterns with metabolic syndrome components in low-income, free-living Brazilian adults. International Journal of Nutrition and Metabolism. 2011; 3 (2): 17-21.
[11]
Mecca MS, Moreto F, Burini FH, Dalanesi RC, McLellan KC, Burini RC. Ten-week lifestyle changing program reduces several indicators for metabolic syndrome in overweight adults. Diabetol Metab Syndr. 2012; 4 (1): 1.
[12]
Talon LC, Oliveira EP, Moreto F, Portero-McLellan KC, Burini RC. Omega-3 fatty acids supplementation decreases metabolic syndrome prevalence after lifestyle modification program. J Functional Foods 2015; 19: 922-8.
[13]
Moreto F, Kano HT, Torezan GA, de Oliveira EP, Manda RM, Teixeira O, et al. Changes in malondialdehyde and C-reactive protein concentrations after lifestyle modification are related to different metabolic syndrome-associated pathophysiological processes. Diabetes Metab Syndr. 2015; 9 (4): 218-22.
[14]
de Oliveira EP, Talon LC, Moreto F, Acerra VMR, McLellan KCP, Burini RC. Additional Benefits of W-3 Oil Supplements on Metabolic Syndrome Care in Exercise Protocol Intervention. In: Wilkins PLW, editor.: Medicine and Science In Sports and Exercise; 2012. p. 272.
[15]
Goncalves LS, Mecca MS, Burini FHP, Dalanesi RC, Peresi VL, Burini RC. Dietary-fibre Adequacy Potentiates Physical Exercises In Metabolic Syndrome Management. In: 3rd World Congress on Exercise is Medicine; San Francisco: Official Journal of the American College of Sports Medicine; 2012. p. 148.
[16]
Burini RC, Nakagaki MS, Michelin E, Burini FHP. Treating Blood Hypertension in a Brazilian Community: Moving from Reactive Homeostatic Model to Proactive Allostatic Healthcare. Ann Clin Hypertens. 2018; 2: 001-16.
[17]
Nakagaki MS, Kano HT, Burini RC. Brazilian Primary Care of T2D with Reactive-Homeostatic and Lifestyle Changing- Allostatic Approaches: A Cost-Effectiveness Data. American Journal of Sports Science. 2018; 6 (3): 98-107.
[18]
Craig CL, Marshall AL, Sjostrom M, Bauman AE, Booth ML, Ainsworth BE, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003; 35 (8): 1381-95.
[19]
World Health Organization (WHO). Global Recommendations on Physical Activity for Health. Geneva (Switzerland): WHO Press. 2010: 24-6.
[20]
Mota JF, Rinaldi AEM, Pereira AF, Maestá N, Scarpin MM, Burini RC. Adaptação do índice de alimentação saudável ao guia alimentar da população brasileira. Revista de Nutrição. 2008; 21: 545-52.
[21]
Heyward V, Stolarczyk L. Avaliação da composição corporal aplicada. 1 edition São Paulo. 2000.
[22]
World Health Organization (WHO). OBESITY Preventing and managing the global epidemic: report of a WHO Consultation on Obesity. Geneva: WHO. 1998.
[23]
Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005; 112 (17): 2735-52.
[24]
Malachias M, Plavnik FL, Machado CA, Malta D, Scala LCN, Fuchs S. 7th Brazilian Guideline of Arterial Hypertension: Chapter 1 - Concept, Epidemiology and Primary Prevention. Arq Bras Cardiol. 2016; 107 (3 Suppl 3): 1-6.
[25]
Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report. Circulation. 2002; 106: 3143.
[26]
Church TS, Thomas DM, Tudor-Locke C, Katzmarzyk PT, Earnest CP, Rodarte RQ, et al. Trends over 5 decades in U.S. occupation-related physical activity and their associations with obesity. PLoS One. 2011; 6 (5): e19657.
[27]
Johnson BL, Nelson JK. Practical measurements for evaluation in physical education. 3rd edition ed. Edina: Burgess Publishing1979.
[28]
Baumgartner TA, Jackson AS. Measurement for evaluation in physical education and exercise science. 8th Edition ed1995.
[29]
Balke B, Ware RW. An experimental study of physical fitness of Air Force personnel. US Armed Forces Med J. 1959; 10 (6): 675-88.
[30]
American Heart Association (AHA). Exercise testing and training of apparently healthy individuals. A handbook for physicians. Circulation. 1972.
[31]
Lakka TA, Laaksonen DE, Lakka HM, Mannikko N, Niskanen LK, Rauramaa R, et al. Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome. Med Sci Sports Exerc. 2003; 35 (8): 1279-86.
[32]
LaMonte MJ, Barlow CE, Jurca R, Kampert JB, Church TS, Blair SN. Cardiorespiratory fitness is inversely associated with the incidence of metabolic syndrome: a prospective study of men and women. Circulation. 2005; 112 (4): 505-12.
[33]
Farrell SW, Cheng YJ, Blair SN. Prevalence of the metabolic syndrome across cardiorespiratory fitness levels in women. Obes Res. 2004; 12 (5): 824-30.
[34]
Wannamethee SG, Shaper AG, Alberti KG. Physical activity, metabolic factors, and the incidence of coronary heart disease and type 2 diabetes. Arch Intern Med. 2000; 160 (14): 2108-16.
[35]
Roberts CK, Hevener AL, Barnard RJ. Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training. Compr Physiol. 2013; 3 (1): 1-58.
[36]
Pereira LE, Michelin E, Corrente JE, Burini RC. Determinants of Low Physical Activity in a Brazilian Community. In: ACSM Annual Meeting; San Diego, CA: Medicine and Science in Sports and Exercise; 2015. p. 242.
[37]
Nakagaki MS, Michelin E, Burini RC. The Effects of A Lifestyle Modification Program on a Leisure Physical Activity and Sedentary Behavior in a Brazilian Low Socioeconomic Community. Journal of Sports Science. 2017; 5: 107-12.
[38]
McLellan KCP, Ramos FMM, Corrente JE, Sloan LA, Burini RC. Evolutionary Roles of Dietary Fiber in Succeeding Metabolic Syndrome (Mets) and its Responses to a Lifestyle Modification Program: A Brazilian Community-based Study. Dietary Fiber: Production Challenges, Food Sources and Health Benefits. 2015: 1ed. New York: Nova Science Publishers; 2015. p. 1-7.
[39]
Takahashi MM, de Oliveira EP, de Carvalho AL, de Souza Dantas LA, Burini FH, Portero-McLellan KC, et al. Metabolic syndrome and dietary components are associated with coronary artery disease risk score in free-living adults: a cross-sectional study. Diabetol Metab Syndr. 2011; 3: 7.
[40]
Ramos FMM, McLellan KCP, Corrente JE, Burini RC. Determinants of the low dietary fiber intake and relationship with Metabolic Syndrome: a Brazilian community-based study. In: Experimental Biology; Boston, MA: The Faseb Journal; 2015. p. 588.15.
[41]
Ilanne-Parikka P, Laaksonen DE, Eriksson JG, Lakka TA, Lindstr J, Peltonen M, et al. Leisure-time physical activity and the metabolic syndrome in the Finnish diabetes prevention study. Diabetes Care. 2010; 33 (7): 1610-7.
[42]
Anderssen SA, Carroll S, Urdal P, Holme I. Combined diet and exercise intervention reverses the metabolic syndrome in middle-aged males: results from the Oslo Diet and Exercise Study. Scand J Med Sci Sports. 2007; 17 (6): 687-95.
[43]
Okura T, Nakata Y, Ohkawara K, Numao S, Katayama Y, Matsuo T, et al. Effects of aerobic exercise on metabolic syndrome improvement in response to weight reduction. Obesity (Silver Spring). 2007; 15 (10): 2478-84.
[44]
Orchard TJ, Temprosa M, Goldberg R, Haffner S, Ratner R, Marcovina S, et al. The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Ann Intern Med. 2005; 142 (8): 611-9.
[45]
Ilanne-Parikka P, Eriksson JG, Lindstrom J, Peltonen M, Aunola S, Hamalainen H, et al. Effect of lifestyle intervention on the occurrence of metabolic syndrome and its components in the Finnish Diabetes Prevention Study. Diabetes Care. 2008; 31 (4): 805-7.
[46]
Camhi SM, Stefanick ML, Katzmarzyk PT, Young DR. Metabolic syndrome and changes in body fat from a low-fat diet and/or exercise randomized controlled trial. Obesity (Silver Spring). 2010; 18 (3): 548-54.
[47]
Roberts CK, Ng C, Hama S, Eliseo AJ, Barnard RJ. Effect of a short-term diet and exercise intervention on inflammatory/anti-inflammatory properties of HDL in overweight/obese men with cardiovascular risk factors. J Appl Physiol (1985). 2006; 101 (6): 1727-32.
[48]
Portero-McLellan KC, Pimentel GD, Corrente JE, Burini RC. Association of fat intake and socioeconomic status on anthropometric measurements of adults. Cad Saude Colet. 2010; 18 (2): 266-74.
[49]
Sasayama K, Ochi E, Adachi M. Importance of both fatness and aerobic fitness on metabolic syndrome risk in Japanese children. PLoS One. 2015; 10 (5): e0127400.
[50]
Schjerve IE, Tyldum GA, Tjonna AE, Stolen T, Loennechen JP, Hansen HE, et al. Both aerobic endurance and strength training programmes improve cardiovascular health in obese adults. Clin Sci (Lond). 2008; 115 (9): 283-93.
[51]
Tjonna AE, Lee SJ, Rognmo O, Stolen TO, Bye A, Haram PM, et al. Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: a pilot study. Circulation. 2008; 118 (4): 346-54.
[52]
Iellamo F, Manzi V, Caminiti G, Vitale C, Castagna C, Massaro M, et al. Matched dose interval and continuous exercise training induce similar cardiorespiratory and metabolic adaptations in patients with heart failure. Int J Cardiol. 2013; 167 (6): 2561-5.
[53]
Boutcher SH. High-intensity intermittent exercise and fat loss. J Obes. 2011; 2011: 868305.
[54]
Gillen JB, Percival ME, Ludzki A, Tarnopolsky MA, Gibala MJ. Interval training in the fed or fasted state improves body composition and muscle oxidative capacity in overweight women. Obesity (Silver Spring). 2013; 21 (11): 2249-55.
[55]
Chang KV, Hung CY, Li CM, Lin YH, Wang TG, Tsai KS, et al. Reduced flexibility associated with metabolic syndrome in community-dwelling elders. PLoS One. 2015; 10 (1): e0117167.
[56]
Whaley MH, Kampert JB, Kohl HW, 3rd, Blair SN. Physical fitness and clustering of risk factors associated with the metabolic syndrome. Med Sci Sports Exerc. 1999; 31 (2): 287-93.
[57]
Katzmarzyk PT, Leon AS, Wilmore JH, Skinner JS, Rao DC, Rankinen T, et al. Targeting the metabolic syndrome with exercise: evidence from the HERITAGE Family Study. Med Sci Sports Exerc. 2003; 35 (10): 1703-9.
[58]
Cornelissen VA, Smart NA. Exercise training for blood pressure: a systematic review and meta-analysis. J Am Heart Assoc. 2013; 2 (1): e004473.
[59]
Duncan GE, Perri MG, Theriaque DW, Hutson AD, Eckel RH, Stacpoole PW. Exercise training, without weight loss, increases insulin sensitivity and postheparin plasma lipase activity in previously sedentary adults. Diabetes Care. 2003; 26 (3): 557-62.
[60]
Dela F, Mikines KJ, von Linstow M, Secher NH, Galbo H. Effect of training on insulin-mediated glucose uptake in human muscle. Am J Physiol. 1992; 263 (6 Pt 1): E1134-43.
[61]
Houmard JA, Shinebarger MH, Dolan PL, Leggett-Frazier N, Bruner RK, McCammon MR, et al. Exercise training increases GLUT-4 protein concentration in previously sedentary middle-aged men. Am J Physiol. 1993; 264 (6 Pt 1): E896-901.
[62]
Evans EM, Van Pelt RE, Binder EF, Williams DB, Ehsani AA, Kohrt WM. Effects of HRT and exercise training on insulin action, glucose tolerance, and body composition in older women. J Appl Physiol (1985). 2001; 90 (6): 2033-40.
[63]
Yfanti C, Nielsen AR, Akerstrom T, Nielsen S, Rose AJ, Richter EA, et al. Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training. Am J Physiol Endocrinol Metab. 2011; 300 (5): E761-70.
[64]
Houmard JA, Tyndall GL, Midyette JB, Hickey MS, Dolan PL, Gavigan KE, et al. Effect of reduced training and training cessation on insulin action and muscle GLUT-4. J Appl Physiol (1985). 1996; 81 (3): 1162-8.
[65]
DiPietro L, Dziura J, Yeckel CW, Neufer PD. Exercise and improved insulin sensitivity in older women: evidence of the enduring benefits of higher intensity training. J Appl Physiol (1985). 2006; 100 (1): 142-9.
[66]
Barwell ND, Malkova D, Moran CN, Cleland SJ, Packard CJ, Zammit VA, et al. Exercise training has greater effects on insulin sensitivity in daughters of patients with type 2 diabetes than in women with no family history of diabetes. Diabetologia. 2008; 51 (10): 1912-9.
[67]
Ostergard T, Andersen JL, Nyholm B, Lund S, Nair KS, Saltin B, et al. Impact of exercise training on insulin sensitivity, physical fitness, and muscle oxidative capacity in first-degree relatives of type 2 diabetic patients. Am J Physiol Endocrinol Metab. 2006; 290 (5): E998-1005.
[68]
Perseghin G, Price TB, Petersen KF, Roden M, Cline GW, Gerow K, et al. Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects. N Engl J Med. 1996; 335 (18): 1357-62.
[69]
Dela F, Larsen JJ, Mikines KJ, Ploug T, Petersen LN, Galbo H. Insulin-stimulated muscle glucose clearance in patients with NIDDM. Effects of one-legged physical training. Diabetes. 1995; 44 (9): 1010-20.
[70]
Atlantis E, Martin SA, Haren MT, Taylor AW, Wittert GA, Members of the Florey Adelaide Male Ageing S. Inverse associations between muscle mass, strength, and the metabolic syndrome. Metabolism. 2009; 58 (7): 1013-22.
[71]
Jurca R, Lamonte MJ, Church TS, Earnest CP, Fitzgerald SJ, Barlow CE, et al. Associations of muscle strength and fitness with metabolic syndrome in men. Med Sci Sports Exerc. 2004; 36 (8): 1301-7.
[72]
Tomeleri CM, Souza MF, Burini RC, Cavaglieri CR, Ribeiro AS, Antunes M, et al. Resistance training reduces metabolic syndrome and inflammatory markers in older women: A randomized controlled trial. J Diabetes. 2017.
[73]
Conceicao MS, Bonganha V, Vechin FC, Berton RP, Lixandrao ME, Nogueira FR, et al. Sixteen weeks of resistance training can decrease the risk of metabolic syndrome in healthy postmenopausal women. Clin Interv Aging. 2013; 8: 1221-8.
[74]
Lemes IR, Ferreira PH, Linares SN, Machado AF, Pastre CM, Netto JJ. Resistance training reduces systolic blood pressure in metabolic syndrome: a systematic review and meta-analysis of randomised controlled trials. Br J Sports Med. 2016.
[75]
Kemmler W, Von Stengel S, Engelke K, Kalender WA. Exercise decreases the risk of metabolic syndrome in elderly females. Med Sci Sports Exerc. 2009; 41 (2): 297-305.
[76]
Stewart KJ, Bacher AC, Turner K, Lim JG, Hees PS, Shapiro EP, et al. Exercise and risk factors associated with metabolic syndrome in older adults. Am J Prev Med. 2005; 28 (1): 9-18.
[77]
Mota JF, Moreto F, Burini FHP, Medina WL, Rimm EB, Burini RC. Effect of physical conditioning with lifestyle intervention on a community-based hyperglycemic-overweight adults. Journal of US-China Medical Science. 2011; 8: 581-87.
[78]
Burini RC, Torezan GA, McLellan KCP. Behavioral risk factors and effects of lifestyle modification on adults with diabetes. A Brazilian community-based study.. Emerging Issues in Medical Diagnosis and Treatment. 2013; 4: 1-20.
[79]
Kano HT, Manda RM, Vilches GN, Burini RC. Behavioral Markers Of Hypertriglyceridemia And Determinants Of Its Normalization By A Lifestyle Modification Program. In: 63 ACSM Annual Meeting; Boston, MA: Medicine and Science in Sports and Exercise; 2016. p. 74.
[80]
Kano HT, Manda RM, Moreto F, Burini FHP, Burini RC. Determinants of high plasma triglyceride levels: a Brazilian community-based study. In: Experimental Biology; Boston, MA: The Faseb Journal; 2015. p. 588.1.
[81]
Burini RC, Kano HT, Nakagaki MS, Nunes CNM, Burini FHP. The lifestyle modification effectiveness in reducing Hypertension in a Brazilian Community: From the epigenetic basis of Ancestral Survival to the Contemporary Lifestyle and Public Health Initiatives. Heighpubs J Clin Hypertens. 2017; 1: 10-31.
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