Volume 6, Issue 2, June 2018, Page: 55-64
Effect of Functional Fitness on Plasma Oxidation Level in Elders: Reduction of the Plasma Oxidants and Improvement of the Antioxidant Barrier
Tania Gamberi, Department of Biomedical, Experimental and Clinical Sciences “Mario Serio”, University of Florence, Florence, Italy
Giulia Gorini, Department of Biomedical, Experimental and Clinical Sciences “Mario Serio”, University of Florence, Florence, Italy
Tania Fiaschi, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Gabriele Morucci, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Simone Pratesi, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Lucio Fittipaldi, Department of Biomedical, Experimental and Clinical Sciences “Mario Serio”, University of Florence, Florence, Italy
Massimo Gulisano, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Pietro Amedeo Modesti, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
Alessandra Modesti, Department of Biomedical, Experimental and Clinical Sciences “Mario Serio”, University of Florence, Florence, Italy
Francesca Magherini, Department of Biomedical, Experimental and Clinical Sciences “Mario Serio”, University of Florence, Florence, Italy
Received: Dec. 19, 2017;       Accepted: Feb. 24, 2018;       Published: Apr. 9, 2018
DOI: 10.11648/j.ajss.20180602.14      View  181      Downloads  13
Abstract
Aging is characterized by a progressive decline in the physiological function due to the gradual alteration of molecules, cells and tissues. Reactive oxygen species (ROS) are the by-product of aerobic metabolism, and their increase is physiologically counteracted by the activation of the antioxidant machinery. A typical hallmark of aging is the imbalance of such equilibrium, due to either an increase of the amount of radicals or a failure of the antioxidant system. Literature reports that physical exercise is able to restore and maintain the homeostasis of oxidants and antioxidants during aging. Recently, growing interest has been turned to functional fitness, a special physical activity aimed to enhance the ability to perform everyday tasks, such as dressing, climbing stairs and preparing meals. The aim of this work was to assess whether a 24 weeks-functional fitness program carried out on 28 elderly participants (57-86 years old) could be able to improve their oxidative status. For this purpose, dROMs (diacron Reactive Oxygen Metabolites) and BAP (Biological Antioxidant Potential) were analysed at the beginning and at the end of the study. Furthermore, both plasma and saliva protein carbonylation levels were explored through proteomics analysis.
Keywords
Aging, Oxidative Stress, Functional Fitness, Protein Carbonylation
To cite this article
Tania Gamberi, Giulia Gorini, Tania Fiaschi, Gabriele Morucci, Simone Pratesi, Lucio Fittipaldi, Massimo Gulisano, Pietro Amedeo Modesti, Alessandra Modesti, Francesca Magherini, Effect of Functional Fitness on Plasma Oxidation Level in Elders: Reduction of the Plasma Oxidants and Improvement of the Antioxidant Barrier, American Journal of Sports Science. Vol. 6, No. 2, 2018, pp. 55-64. doi: 10.11648/j.ajss.20180602.14
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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